As of the printing of Anabolics 2000 I reported no preparation that was being made in a dosage over 5mg, but just two years later we now have several preparations carrying l0mg, and one weighing in with an incredible 25mg per tablet. That equates to 5 normal Dianabol tablets worth of steroid, which I think is clearly indicative of a new trend in steroid manufacturing. Understanding that the steroid market in many parts of the world really caters to athletes, many producers have seemingly been rushing to release newer and more shockingly high dosed products. Not only Dianabol, but also versions of Testosterone cypionate, Testosterone propionate, nandrolone decanoate, nandrolone laurate, stanozolol, boldenone undecylenate and oxandrolone have been released in the past two years carrying higher dosages than ever before seen commercially. With the extremely lucrative market for steroids at this time there is little doubt that this trend will continue.
After the Kefauver Harris Amendment was passed in 1962, the . FDA began the DESI review process to ensure the safety and efficacy of drugs approved under the more lenient pre-1962 standards, including Dianabol.  In 1965, the FDA pressured CIBA to further document its legitimate medical uses, and re-approved the drug for treating post-menopausal osteoporosis and pituitary-deficient dwarfism .  After CIBA's patent exclusivity period lapsed, other manufacturers began to market generic metandienone in the .